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Infigratinib, MedChemExpress

Product Code. 16448855
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Product Code. 16448855 Supplier Medchem Express Supplier No. HY13311

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Description

MedChemExpress Infigratinib (BGJ-398; NVP-BGJ398) is a potent inhibitor of the FGFR family with IC50s of 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively.

Infigratinib (BGJ-398

Specifications

Chemical Name or Material Infigratinib
CAS 872511-34-7
Color White
Purity Grade Notes Research
Molecular Formula C26H31Cl2N7O3
Quantity 10 mg
Synonym BGJ-398 NVP-BGJ398
Solubility Information DMSO : 12 mg/mL (21.41 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (insoluble)
SMILES ClC1=C(C(Cl)=C(C=C1OC)OC)NC(N(C2=CC(NC3=CC=C(C=C3)N4CCN(CC4)CC)=NC=N2)C)=O
Molecular Weight (g/mol) 560.48
Formula Weight 560.48
Percent Purity 98.69%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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