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Invitrogen™ INHA Polyclonal Antibody

Description
Immunogen sequence: CPLCTCSARP EATPFLVAHT RTRPPSGGER ARRSTPLMSW PWSPSALRLL QRPPEEPAAH ANCHRVALNI SFQELGWERW IVYPPSFIFH YCHGGCGLHI P Positive Samples: Rat testis.
The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone.
Specifications
Specifications
| Antigen | INHA |
| Applications | ELISA, Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 0.45 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | INHA |
| Gene Accession No. | P05111, P17490, Q04997 |
| Gene Alias | A inhibin subunit; A-inhibin subunit; AW555078; IHA; Inha; inhibin; inhibin alpha; inhibin alpha chain; inhibin alpha subunit |
| Gene Symbols | INHA |
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Nom du produit
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