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Invitrogen™ INO80 Polyclonal Antibody
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Product Code. 15918054
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. Quantity unitSize
15918054 100 μL 100µL
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Product Code. 15918054 Supplier Invitrogen™ Supplier No. PA565296

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: KRQQRKLNFLI TQTELYAHFM SRKRDMGHDG IQEEILRKLE DSSTQRQIDI GGGVVVNITQ EDYDSNHFKA QALKNAENAY HIHQARTRSF DEDAKESR Highest antigen sequence identity to the following orthologs - mouse 100%, rat 100%.

DNA helicase and probable main scaffold component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair; according to PubMed:20687897 the contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation. Recruited by YY1 to YY1-activated genes, where it acts as an essential coactivator. Binds DNA. In vitro, has double-stranded DNA-dependent ATPase activity. Involved in UV-damage excision repair, DNA replication and chromosome segregation during normal cell division cycle.
TRUSTED_SUSTAINABILITY

Specifications

Antigen INO80
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Ino80
Gene Accession No. Q9ULG1
Gene Alias 2310079N15Rik; 4632409L19Rik; Chromatin-remodeling ATPase INO80; DNA helicase INO80; DNA helicase-related INO80 complex homolog 1; DNA helicase-related protein INO80; hINO80; homolog of yeast INO80; Ino80; INO80 complex homolog 1; INO80 complex subunit; INO80 complex subunit A; INO80 homolog; INO80 homolog (S. cerevisiae); INO80A; Inoc1; KIAA1259; putative DNA helicase INO80 complex homolog 1; RGD1310969; yeast INO80-like protein
Gene Symbols Ino80
Host Species Rabbit
Immunogen Recombinant Human INO80. Recombinant protein control fragment (Product #RP-106007).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54617
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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