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Invitrogen™ INO80 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA565301

Product Code. 15968054

  • € 558.00 / 100µL

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Description

Description

Immunogen sequence: CTELAKPLYLQ YLERALRLDH FLRQTSAIFN RNISSDDSED GLDDSNPLLP QSGDPLIQVK EEPPNSLLGE TSGAGSSGML NTYSLNGVLQ S Highest antigen sequence identity to the following orthologs - mouse 93%, rat 95%.

DNA helicase and probable main scaffold component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair; according to PubMed:20687897 the contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation. Recruited by YY1 to YY1-activated genes, where it acts as an essential coactivator. Binds DNA. In vitro, has double-stranded DNA-dependent ATPase activity. Involved in UV-damage excision repair, DNA replication and chromosome segregation during normal cell division cycle.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

INO80
Polyclonal
Unconjugated
Ino80
2310079N15Rik; 4632409L19Rik; Chromatin-remodeling ATPase INO80; DNA helicase INO80; DNA helicase-related INO80 complex homolog 1; DNA helicase-related protein INO80; hINO80; homolog of yeast INO80; Ino80; INO80 complex homolog 1; INO80 complex subunit; INO80 complex subunit A; INO80 homolog; INO80 homolog (S. cerevisiae); INO80A; Inoc1; KIAA1259; putative DNA helicase INO80 complex homolog 1; RGD1310969; yeast INO80-like protein
Rabbit
Antigen affinity chromatography
RUO
54617
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
ChIP Assay, Immunocytochemistry
0.1 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q9ULG1
Ino80
Recombinant Human INO80. Recombinant protein control fragment (Product #RP-106009).
100 μL
Primary
Human
Antibody
IgG
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