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Integrin beta 3/CD61 Antibody (Y2/51), DyLight 594, Novus Biologicals™
Mouse Monoclonal Antibody
Brand: Novus Biologicals NBP2-54418DL594
This item is not returnable.
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Description
Integrin beta 3/CD61 Monoclonal specifically detects Integrin beta 3/CD61 in Human samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
Specifications
| Integrin beta 3/CD61 | |
| Monoclonal | |
| DyLight 594 | |
| 50mM Sodium Borate with 0.05% Sodium Azide | |
| ITGB3 | |
| Phytohemagglutinin (PHA)-stimulated peripheral blood cells | |
| 0.1 mL | |
| Angiogenesis, Cancer, Cell Biology, Cellular Markers, Extracellular Matrix, Immunology, Phospho Specific, Signal Transduction, Stem Cell Markers | |
| Reacts with human integrin beta3 (GPIIIa, vitronectin receptor beta chain). It associates with the IIb-chain (CD41) to form the GpIIb/GpIIIa complex (CD41/CD61).The CD41/CD61 complex appears early in megakaryocyte maturation. The activated CD41/CD61 complex is a receptor for von Willebrand factor, soluble fibrinogen, fibronectin, vitronectin and thrombospondin. It plays a central role in platelet activation and aggregation. The CD51/CD61 is implicated in tumor metastasis and adenoviral infection. The antibody detects platelets in smears of blood and bone marrow, as well as megakaryocytes in frozen sections and cell smears. The antibody is useful for classification of megakaryoblastic leukemia. | |
| Store at 4°C in the dark. |
| Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin) | |
| Y2/51 | |
| Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin | |
| CD61, CD61 antigen, GP3Aplatelet glycoprotein IIIa, GPIIIaintegrin beta-3, integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61), ITG B3, Platelet membrane glycoprotein IIIa | |
| Mouse | |
| Protein A or G purified | |
| RUO | |
| Primary | |
| Human | |
| IgG1 κ |
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