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Integrin beta 4/CD104 Antibody (UM-A9), Allophycocyanin/Cy7, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-34507APCCY7

Product Code. 18121832

  • € 610.00 / 0.10mL

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This item is not returnable. View return policy

Description

Description

Integrin beta 4/CD104 Monoclonal specifically detects Integrin beta 4/CD104 in Human samples. It is validated for Flow Cytometry.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Integrin beta 4/CD104
Monoclonal
APC-Cyanine7
PBS with 0.05% Sodium Azide
ITGB4
Human squamous cell carcinoma (UM-SCC1)
0.1 mL
Primary
Recognizes a protein of 205kDa, which is identified as integrin beta-4 (ITGB4). Its epitope is localized in the extracellular domain of ITGB4 protein. Integrins are heterodimers comprised of alpha and beta subunits, that are non-covalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta-4 subunit, a receptor for the laminins. This subunit tends to associate with alpha-6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Store at 4°C in the dark. Do not freeze.
Flow Cytometry
UM-A9
Flow Cytometry
CD104, CD104 antigen, GP150, integrin beta-4, integrin beta-4 subunit, integrin, beta 4
Mouse
Protein A or G purified
Adaptive Immunity, Immunology, Phospho Specific, Signal Transduction
3691.0
Human
IgG2a κ
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