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Invitrogen™ INTU Polyclonal Antibody
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Product Code. 15715681 Shop All Thermo Scientific Products
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100 μL
Unit Size:
100µL
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15715681 100 μL 100µL
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Product Code. 15715681 Supplier Invitrogen™ Supplier No. PA557785

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: NDNGPVSILK HQSNQKTGVI VQQRYKDVNV YVNPKKLTVI KAKEQLKLLE VLVGIIHQTK WSWRRTGKQG DGERLVVHGL LPGGSAMKSG QVLIGDV Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 82%.

Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling. Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (PubMed:27158779). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen INTU
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene INTU
Gene Accession No. Q9ULD6
Gene Alias 9230116I04Rik; 9430087H23Rik; homolog of inturned; INT; Intu; Inturned planar cell polarity effector homolog; inturned planar cell polarity effector homolog (Drosophila); inturned planar cell polarity protein; KIAA1284; mKIAA1284; PDZ domain containing 6; PDZ domain-containing protein 6; PDZD6; PDZK6; Protein inturned
Gene Symbols INTU
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human INTU. Recombinant protein control fragment (Product #RP-103774).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27152
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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