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  6. Thermo Scientific Chemicals Ionomycin, 96%

Thermo Scientific Chemicals Ionomycin, 96%

Product Code. 15414829
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Quantity:
1 mg
5 mg
Unit Size:
1mg
5mg
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Código de producto. 15414829

Marca: Thermo Scientific Chemicals J62448.M^

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Descripción

Highly selective and potent calcium ionophore | CAS: 56092-81-0 | C41H72O9, C41H72O9 | 709.02 g/mol

Ionomycin free acid is a beneficial tool in research to raise intracellular calcium levels. Also this antibiotic can be used to study the calcium transport across the plasma membrane. It has been shown to induce central demyelination , inhibit adrenal bovine TREK-1 channels , and to regulate cell division of mature human B cells . It is used to study the effects of calcium flux on endoplasmic reticulum (ER) stress, mitochondrial stress and intrinsic apoptosis mechanisms. It is also used to stimulate the intracellular production of the cytokines, interferon, perforin, IL-2, and IL-4 usually in conjunction with PMA.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

TRUSTED_SUSTAINABILITY

Identificadores de productos químicos

CAS 56092-81-0
Molecular Formula C41H72O9

Especificaciones

Quantity 1 mg
Description Colorless
Content And Storage -30°C to -10°C
For Use With (Application) Highly selective and potent calcium ionophore
Formula Weight 709.02
Odor Alcohol-like
Product Type Ionomycin
Form Solution in ethanol
Beilstein 3642126
InChI Key PGHMRUGBZOYCAA-OJFQOPKISA-N
SMILES C[C@H](CCC(O)=O)C[C@H](C)C[C@H](C)C(=O)\C=C(/O)[C@H](C)C[C@H](C)C\C=C\[C@@H](C)[C@@H](O)[C@@H](C)[C@@H](O)CC1CC[C@](C)(O1)C1CC[C@](C)(O1)[C@@H](C)O
IUPAC Name (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-trihydroxy-22-[(2S,5'S)-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl-[2,2'-bioxolan]-5-yl]-4,6,8,12,14,18,20-heptamethyl-9-oxodocosa-10,16-dienoic acid
Molecular Weight (g/mol) 709.02
Assay 98%
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Seguridad y manipulación

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Nombre del producto
  • Ionomycin
 Palabra de advertencia
  • Danger
 Clasificación
  • Serious eye damage/eye irritation Category 2
  • Flammable liquid Category 2
 Indicaciones de peligro
  • H225-Highly flammable liquid and vapour.
  • H319-Causes serious eye irritation.
 Consejos de prudencia
  • P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P264-Wash face, hands and anyexposed skin thoroughly after handling.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P337+P313-If eye irritation persists: Get medical advice/attention.
 Otros peligros
  • MIXTURE LIST-Contains : ethanol, ionomycin
SDS

RUO – Research Use Only

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