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Invitrogen™ IPAB Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5144414
This item is not returnable.
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Description
IPAB Polyclonal Antibody for Western Blot, ELISA
Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells (PubMed:10545510, PubMed:17367391). IpaB/SctE and IpaC/SctB are inserted into the host membrane where they form a pore and allow the translocation of effector proteins into the cytosol of target cells (PubMed:10545510, PubMed:17367391, PubMed:34809452). Interaction with IpaD/SctA at needle tips leads to the formation of the MxiH/SctF-IpaD/SctA-IpaB/SctE ternary complex, which is essential for host cell sensing (PubMed:17367391, PubMed:19433542). Interaction of IpaB/SctE with host membrane lipids promotes recruitment of IpaC/SctB at the needle tip concomitant with translocon insertion into the host membrane and type III secretion induction (PubMed:19433542).
Specifications
| IPAB | |
| Polyclonal | |
| Unconjugated | |
| sctE | |
| ipaB | |
| Rabbit | |
| Protein G | |
| RUO | |
| 1238055 | |
| -20°C or -80°C if preferred | |
| Liquid |
| ELISA, Western Blot | |
| 3.904 mg/mL | |
| PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4 | |
| P18011 | |
| sctE | |
| Recombinant Shigella flexneri IPAB protein (1-312aa). | |
| 100 μL | |
| Primary | |
| Bacteria | |
| Antibody | |
| IgG |
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