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IQGAP1 Monoclonal Antibody (OTI6E1), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA809921
This item is not returnable.
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Description
DISP2 is the second of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored Hedgehog from producing cells. Hedgehog is a major player in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis and the DISP proteins have been implicated in these pathways. Recently, it has been shown that DISP2 is translationally regulated by the microRNA miR-214 in zebrafish. Expression of this miRNA decreased DISP2 promoter activity in vitro and its overexpression in zebrafish resulted in a phenotype identical to that observed by DISP2 mutants.Specifications
| IQGAP1 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| P46940 | |
| IQGAP1 | |
| Human recombit protein fragment corresponding to amino acids 464-609 of human IQGAP1 produced in E.coli. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Immunohistochemistry (Paraffin), Western Blot | |
| OTI6E1 | |
| Unconjugated | |
| IQGAP1 | |
| HUMORFA01, SAR1, p195 | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 8826 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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