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Invitrogen™ IRAK4 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5144196
This item is not returnable.
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Description
IRAK4 Polyclonal Antibody for Western Blot, ELISA, IP
IL-1 receptor associated kinases (IRAKs) are serine/threonine kinases involved in signaling via Toll/IL-1 pathways. Overexpression of IRAK-4 activates NF-kappa-B and MAPK pathways. IRAK-4 interacts with and phosphorylates IRAK-1. IRAK-4-deficient animals are completely resistant to the challenge with LPS. Animals and humans lacking IRAK-4 are impaired in their responses to viral and bacterial challenges. Members in IRAK/Pelle family play a central role in IL-1R/TLR mediated inflammatory responses and in innate immunity.
Specifications
| IRAK4 | |
| Polyclonal | |
| Unconjugated | |
| IRAK4 | |
| 8430405M07Rik; 9330209D03Rik; interleukin 1 receptor associated kinase 4; interleukin-1; interleukin-1 receptor-associated kinase 4; IPD1; Irak4; IRAK-4; NY-REN-64; REN64; renal carcinoma antigen NY-REN-64 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 51135 | |
| -20°C or -80°C if preferred | |
| Liquid |
| ELISA, Immunoprecipitation, Western Blot | |
| 0.36 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q9NWZ3 | |
| IRAK4 | |
| Recombinant Human Interleukin-1 receptor-associated kinase 4 protein (1-220AA). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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