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Invitrogen™ IRF7 Recombinant Rabbit Monoclonal Antibody (23GB2925), Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA552510
This item is not returnable.
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Description
Interferons (IFNs) are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms. During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-a/b genes. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. IRF7 play a major role in the innate immune pathway, interacting with the Toll-like receptor (TLR) adaptor proteins MyD88 and Tirp/TRAM and functioning as an intermediate TLR4 and TLR9 signaling. There are at least four differentially spliced isoforms of IRF7, although their function has not been clearly established.
Specifications
| IRF7 | |
| Recombinant Monoclonal | |
| 1.5 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P70434, Q92985 | |
| IRF7 | |
| A synthesized peptide derived from human IRF7 (200-238AA). | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
| Flow Cytometry, Western Blot, Immunocytochemistry | |
| 23GB2925 | |
| Unconjugated | |
| IRF7 | |
| IMD39; Interferon regulatory factor 7; interferon regulatory factor-7H; Irf7; IRF-7; IRF7A; IRF7B; IRF7C; IRF7H; IRF-7H | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 293624, 3665, 54123 | |
| -20°C | |
| Liquid |
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