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  7. 30195171

Invitrogen™ IRF9 Monoclonal Antibody (K70047_18H9), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA555884

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Product Code. 30195171

  • € 524.00 / 50µg

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Description

Description

Sequence of this protein is as follows: REDQDAAFFK AWAIFKGKYK EGDTGGPAVW KTRLRCALNK SSEFKEVPER GRMDVAEPYK VYQLLPPGIV SGQPGTQKVP SKRQHSSVSS ERKEEEDAMQ NCTLSPSVLQ DSLNNEEEGA SGGAVHSDIG SSSSSSSPEP QEVTDTTEAP FQGDQRSLEF

Transcription factor that plays an essential role in anti-viral immunity. It mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. [UniProt].
TRUSTED_SUSTAINABILITY
Specifications

Specifications

IRF9
Monoclonal
1 mg/mL
PBS with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Q00978
IRF9
Recombinant human IRF9 (immunogen range is 51-210).
50 μL
Primary
Human
Antibody
IgG1
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
K70047_18H9
Unconjugated
IRF9
gamma 48kDa; IFN alpha responsive transcription factor subunit; IFN-alpha-responsive transcription factor subunit; interferon dependent positive acting transcription factor 3 gamma; interferon regulatory factor 9; Interferon-stimulated gene factor 3 gamma; interferon-stimulated transcription factor 3; interferon-stimulated transcription factor 3, gamma (48kD); interferon-stimulated transcription factor 3, gamma 48kDa; IRF9; Irf-9; ISGF3; ISGF-3 gamma; ISGF3 p48 subunit; ISGF3G; p48; transcriptional regulator ISGF3 subunit gamma; Unknown (protein for MGC:126912); Unknown (protein for MGC:92097); zgc:92097
Mouse
Protein A
RUO
10379
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
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