missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. Invitrogen™ ITGB1BP2 Monoclonal Antibody (K52028_12C5), Invitrogen™

Invitrogen™ ITGB1BP2 Monoclonal Antibody (K52028_12C5), Invitrogen™

Product Code. p-200088715
Change view
Click to view available options
Quantity:
50 μL
200 μL
Unit Size:
200µg
50µg
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
30198233 50 μL 50µg
30206676 200 μL 200µg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
This item is not returnable. View return policy
Product Code. 30198233 Supplier Invitrogen™ Supplier No. MA555642

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Mouse Monoclonal Antibody

Sequence of this protein is as follows: EAPQPEGPAT SSSLQEQKPL NVIPKSAETL RRERPKSELP LKLLPLNISQ ALEMALEQKE LDQEPGAGLD SLIRTGSSCQ NPGCDAVYQG PESDATPCTY HPGAPRFHEG MKSWSCCGIQ TLDFGAFLAQ PGCRVGRHDW GKQLPASCRH DWHQTDSLVV VTVYGQIPLP AFNWVKASQT ELHVHIVFDG NRVFQAQMKL WGVINVEQSS VFLMPSRVEI SLVKADPGSW AQLEHPDALA KKARAGVVLE MDEEESDDSD DDLSWTEEEE

Integrin beta-1 binding protein 2 (ITGB1BP2), commonly referred to as Melusin, is a gene located on human chromosome 8p21.3. ITGB1BP2 is known for its role in cardiac muscle function, encoding a protein that interacts with integrin β1, which is essential for integrin signaling pathways. This gene is implicated in hypertrophic cardiomyopathy and dilated cardiomyopathy, conditions that affect heart muscle structure and function. ITGB1BP2 gene variations have been observed in families with hypertension or primary hypertrophic cardiomyopathy, although clear genotype/phenotype correlations were not conclusively established. Notably, a specific missense mutation in ITGB1BP2, involving alanine-to-glycine substitution at position 313, has been identified in patients with dilated cardiomyopathy. Melusin, the protein encoded by ITGB1BP2, plays a crucial role in mechanotransduction processes, influencing cellular responses to mechanical stress, which is particularly important in cardiac tissue adaptation and repair mechanisms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ITGB1BP2
Applications Immunoprecipitation, Western Blot
Classification Monoclonal
Clone K52028_12C5
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Gene ITGB1BP2
Gene Accession No. Q9UKP3
Gene Alias Chordc3; integrin beta 1 binding protein (melusin) 2; integrin beta 1 binding protein 2; integrin beta-1-binding protein 2; integrin subunit beta 1 binding protein 2; ITGB1BP; Itgb1bp2; Melusin; MGC119214; MSTP015; RGD1565015
Gene Symbols ITGB1BP2
Host Species Mouse
Immunogen Recombinant human ITGB1BP2 (immunogen range is 71-340).
Purification Method Protein A
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26548, 317258
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.