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ITPR3 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA588758
Additional Details : Weight : 0.01000kg
Description
Immunogen sequence: EGSEAYQRCE SGGFLSKLIQ HTKDLMESEE KLCIKVLRTL QQMLLKKTKY GDRGNQLRKM LLQNYLQNRK STSRGDLPDP IGTGLDPDWS AIAATQCRLD KEGATKLVCD LITSTKNEKI FQESIGLAIH LLDGGNTEIQ KSFHNLMMSD KKSERFFKVL HDRMKRAQQE TKSTVAVNMN DLGSQPHEDR EPVDPTTKGR VASFSIPGSS SRYSLGPSLR RGHEVSERVQ SSEMGTSVLI M; Positive Samples: HeLa, LO2, HepG2; Cellular Location: Endoplasmic reticulum membrane, Multi-pass membrane protein
This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth.Specifications
| ITPR3 | |
| Polyclonal | |
| Unconjugated | |
| ITPR3 | |
| ITPR3 | |
| Recombit fusion protein containing a sequence corresponding to amino acids 1630-1870 of human ITPR3 | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
| Immunofluorescence, Western Blot | |
| 5.95 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q14573 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 3710 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |