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Ivosidenib, MedChemExpress

Product Code. 16497618
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Product Code. 16497618

Brand: Medchem Express HY18767

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Description

MedChemExpress Ivosidenib (AG-120) is an orally active inhibitor of isocitrate dehydrogenase 1 mutant (mIDH1) enzyme, it exhibits profound d-2-hydroxyglutatrate (2-HG) lowering in vivo. Ivosidenib (AG-120) has the potential for AML therapy due to its acceptable safety profile and clinical activity.

Ivosidenib (AG-120) is an orally active inhibitor of isocitrate dehydrogenase 1 mutant (mIDH1) enzyme, it exhibits profound d-2-hydroxyglutatrate (2-HG) lowering in vivo. Ivosidenib (AG-120) has the potential for AML therapy due to its acceptable safety profile and clinical activity.

Specifications

Chemical Name or Material Ivosidenib
CAS 1448347-49-6
Color White
Purity Grade Notes Research
Molecular Formula C28H22ClF3N6O3
Quantity 10 mg
Synonym AG-120
Solubility Information DMSO : ≥ 39 mg/mL (66.90 mM)
SMILES ClC1=C([C@H](N(C2=CC(F)=CN=C2)C([C@H]3N(C4=NC=CC(C#N)=C4)C(CC3)=O)=O)C(NC5CC(F)(F)C5)=O)C=CC=C1
Molecular Weight (g/mol) 582.96
Formula Weight 582.96
Percent Purity 98.01%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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