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STEMCELL Technologies IWP-3

Product Code. 17170082
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10 mg
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10mg
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Product Code. 17170082 Supplier STEMCELL Technologies Supplier No. 72544

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Description

WNT pathway inhibitor; Inhibits Porcupine

  • Inhibitor of WNT Production-3 (IWP-3) inhibits WNT signaling by inactivating Porcupine, a membrane-bound O-acyltransferase responsible for palmitoylating WNT proteins, which is essential for WNT signaling ability and secretion (Chen et al.) IWP-3 impairs WNT pathway activity in vitro with an IC50 value of 40 nM (Chen et al.)
  • Promotes cardiomyocyte differentiation from human embryonic stem cells that have been induced to mesoderm by addition of BMP4 and Activin A (Willems et al.)

Specifications

CAS 687561-60-0
Synonym Inhibitor of Wnt Production-3
Quantity 10 mg
Molecular Formula C22H17FN4O2S3
Purity ≥98%
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