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Tocris Bioscience™ J 104129 fumarate
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Product Code. 18055012
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10 mg
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10mg
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Product Code. 18055012 Supplier Tocris Bioscience™ Supplier No. 2507/10

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Potent and selective M3 antagonist

Potent M3 muscarinic receptor antagonist that displays ∽ 120-fold selectivity over M2 receptors (Ki values are 4.2, 19 and 490 nM for human M3, M1 and M2 receptors respectively). Exhibits > 250-fold bronchial selectivity; inhibits ACh-induced bronchoconstriction but not ACh-induced bradycardia (KB values are 3.3 and 170 nM for rat trachea M3 and rat right atria M2 receptors respectively).
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Specifications

CAS 257603-40-0
Quantity 10 mg
Molecular Formula C28H40N2O6
Formula Weight 500.63
Purity >99%
Molecular Weight (g/mol) 500.636
Chemical Name or Material J 104129 fumarate
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