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Tocris Bioscience™ J 113863

Product Code. 30001443
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30001443 1 mg 1mg
18065492 10 mg 10mg
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Product Code. 30001443 Supplier Tocris Bioscience™ Supplier No. 2595/1

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144.50 EUR valid until 2026-03-31
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Description

Potent CCR1 chemokine receptor antagonist

Potent chemokine receptor 1 (CCR1) antagonist (IC50 values are 0.9 and 5.8 nM for human and mouse CCR1 receptors respectively). Also displays high selectivity for human but not mouse CCR3 receptors (IC50 values are 0.58 and 460 nM respectively). Improves paw inflammation, joint damage and dramatically reduces cell infiltration into joints in collagen-induced arthritis in mice.

Isomer also available.

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 353791-85-2
Molecular Formula C30H37Cl2IN2O2

Specifications

Quantity 1 mg
Formula Weight 655.44
Purity >98%
Molecular Weight (g/mol) 655.442
Chemical Name or Material J 113863
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