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Invitrogen™ JAB1 Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA582170
This item is not returnable.
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Description
Immunogen sequence: ANNMQEAQSI DEIYKYDKKQ QQEILAAKPW TKDHHYFKYC KISALALLKM VMHARSGGNL EVMGLMLGKV DGETMIIMDS FALPVEGTET RVNAQAAAYE YMAAYIENAK QVGRLENAIG WYHSHPGYGC WLS Highest antigen sequence indentity to the following orthologs: Rat - 100%, Mouse - 100%.
JAB-1 is a 38 kDa protein which was originally described as a coactivator for cJUN. It is present in a large protein complex called the 'Signalosome', which has been proposed to play a signaling role in mammalian cells. This protein complex appears to be analogous to the COP9 complex in plants, which is important in light-mediated plant development. Although the specific function of JAB-1 in this complex is unclear, it has recently been implicated in targeting proteins for degradation by the proteasome.
Specifications
| JAB1 | |
| Polyclonal | |
| Unconjugated | |
| Cops5 | |
| 38 kDa Mov34 homolog; AI303502; COP9 (constitutive photomorphogenic) homolog, subunit 5; COP9 (constitutive photomorphogenic) homolog, subunit 5 (Arabidopsis thaliana); COP9 complex S5; COP9 constitutive photomorphogenic homolog subunit 5; COP9 signalosome complex subunit 5; COP9 signalosome subunit 5; Cops5; CSN5; JAB1; Jun activation domain-binding protein 1; Jun coactivator; Kic2; Kip1 C-terminus-interacting protein 2; MGC3149; Mov34; MOV-34; SGN5; signalosome subunit 5; testis secretory sperm-binding protein Li 231m | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 10987, 26754, 312916 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 0.1 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| O35864, Q92905 | |
| Cops5 | |
| Recombinant protein corresponding to Human COPS5. Recombinant protein control fragment (Product #RP-102506). | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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