missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ JAM-A (CD321) Monoclonal Antibody (M.Ab.F11)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA549041
This item is not returnable.
View return policy
Description
The monoclonal antibody M.Ab.F11 recognizes junctional adhesion molecule-A (JAM-A) also known as the human platelet F11-Receptor (F11R) or JAM-1.
CD321 (F11R, JAM-1, JAM-A) is a cell-surface adhesion molecule belonging to the Ig superfamily of receptors. CD321 is a 32-41 kD glycoprotein, possessing two extracellular Ig-like domains, a transmembrane region, and a short cytosolic tail. The protein assembles at the membrane as a homodimer, and can associate laterally with other membrane proteins including integrins. CD321 is expressed on a variety of cell types, including leukocytes, platelets, erythrocytes, stem cells, epithelial and endothelial cells, and plays a role in mediating cell-cell contact. CD321 can be found in close proximity to several components of epithelial tight junctions, including ZO-1 and occludin. CD321 is involved in the maintenance of epithelial and endothelial barriers, hematopoiesis, angiogenesis, and tumor proliferation, invasion, and metastasis.
Specifications
| JAM-A (CD321) | |
| Monoclonal | |
| 100 μg/mL | |
| PBS with 0.1% BSA and no preservative | |
| Q9Y624 | |
| F11r | |
| Human platelet membranes. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Flow Cytometry, Functional Assay, Inhibition Assays, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry | |
| M.Ab.F11 | |
| Unconjugated | |
| F11r | |
| 9130004G24; AA638916; BV11 antigen; CD321; ESTM33; F11 R; F11 receptor; F11 receptor/F11R; F11R; JAM; JAM1; JAM-1; JAMA; JAM-A; Jcam; Jcam1; junction cell adhesion molecule A; junction cell adhesion molecule1; junctional adhesion molecule 1; Junctional adhesion molecule A; KAT; Ly106; PAM-1; Platelet adhesion molecule 1; platelet F11 receptor; UNQ264/PRO301 | |
| Mouse | |
| Protein G | |
| RUO | |
| 50848 | |
| 4°C | |
| Liquid |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction