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Tocris Bioscience™ JPS036

Product Code. 30040317
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5 mg
Unit Size:
5mg
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Product Code. 30040317 Supplier Tocris Bioscience™ Supplier No. 8085/5

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Description

Selective HDAC3 Degrader (PROTAC™)

JPS036 is a selective HDAC3 Degrader (PROTAC™) (DC50 = 440 nM; Dmax = 77 %). JPS036 comprises a benzamide-based compound joined by a linker to a Von Hippel Lindau (VHL) E3 ligase ligand.

Negative control JPS016NC also available.

PROTAC™ is a registered trademark of Arvinas Operations, Inc., and is used under license.

TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material (2S,4R)-N-[2-[[12-[[4-[(2-Aminophenyl)carbamoyl]phenyl]amino]-12-oxododecyl]oxy]-4-(4-methylthiazol-5-yl)benzyl]-1-[(S)-2-(1-fluorocyclopropan-1-ylcarbonylamino)-3,3-dimethylbutanoyl]-4-hydroxypyrrolidine-2-carboxamide
CAS 2669785-85-5
Quantity 5 mg
Target Active Degraders
Molecular Formula C51H66FN7O7S
Purity 0.98
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