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Invitrogen™ JunD Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5120140
This item is not returnable.
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Description
Positive test controls include: HeLa, Jurkat, 293T, HepG2, Mouse kidney, Mouse liver, Mouse pancreas, Mouse testis, Rat liver. The target is usually found in the following locations: Nucleus. Immunogen sequence: METPFYGDEA LSGLGGGASG SGGSFASPGR LFPGAPPTAA AGSMMKKDAL TLSLSEQVAA ALKPAAAPPP TPLRADGAPS AAPPDGLLAS PDLGLLKLAS PELERLIIQS NGLVTTTPTS SQFLYPKVAA SEEQEFAEGF VKALEDLHKQ NQLGAGAAAA AAAAAAGGPS GTATGSAPPG ELAPAAAAPE.
JunD is a transcription factor which is coded by JunD gene. JunD transcriptional activity is modulated by phosphorylation in response to cellular stress via the c-Jun N terminal kinase (JNK)/Stress-Activated Protein Kinase (SAPK) family of protein kinase. Jun proteins are capable of forming dimers with Fos, ATF and CREB family transcription factors to form the AP-1 complex that differentially regulates a variety of target genes involved in cellular growth, proliferation, differentiation and apoptosis. Also, JunD plays an important role in metabolism via modulation of IGF-1 signaling pathway.
Specifications
| JunD | |
| Polyclonal | |
| Unconjugated | |
| JUND | |
| activator protein 1; AP1; AP-1; JUN D; jun D proto-oncogene; Jun proto-oncogene related gene d; Jun proto-oncogene related gene d1; Jund; Jun-d; JunD proto-oncogene, AP-1 transcription factor subunit; Jund1; JunD-FL isoform; Oncogene Jun-D; Transcription factor jun-D | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 16478, 24518, 3727 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Immunohistochemistry (Paraffin), Western Blot | |
| 0.81 mg/mL | |
| PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 | |
| P15066, P17535, P52909 | |
| JUND | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human JunD (NP_005345.3). | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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