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Tocris Bioscience™ JWH 133

Product Code. 18014862
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10 mg
Unit Size:
10mg
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Product Code. 18014862 Supplier Tocris Bioscience™ Supplier No. 1343/10

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Description

Potent and selective CB2 agonist

JWH 133 is a potent CB2 selective agonist (Ki = 3.4 nM). Approx. 200-fold selective over CB1 receptors. Active in vivo, reducing spasticity in a murine model of multiple sclerosis. Activity also enhances the release of IL-10 by LPS/IFN-γ-stimulated macrophages and results in downregulation of the IL-12 subunit p40.
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Specifications

Chemical Name or Material (6aR,10aR)-3-(1,1-Dimethylbutyl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran
CAS 259869-55-1
Quantity 10 mg
Target Cannabinoid R2/CB2 Agonists
Molecular Formula C22H32O
Purity 98%
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