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Tocris Bioscience™ JX 06
GREENER_CHOICE

Potent and selective pyruvate dehydrogenase kinase (PDK) 1/2/3 inhibitor

Brand:  Tocris Bioscience™ 5845/10

Encompass

Product Code. 15797136

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Description

Description

JX 06 is a potent and selective pyruvate dehydrogenase kinase (PDK) 1/2/3 inhibitor (IC50 values are 49, 101 and 313 nM for PDK1, PDK2 and PDK3, respectively). Exhibits selectivity for PDK1/2/3 over PDK4 and a panel of 323 other kinases. Suppresses A549 lung cancer cell proliferation in vitro. Reduces tumor volume of A549 xenografts in mice.
Specifications

Specifications

Bis(morpholinothiocarbonyl) disulfide
729-46-4
10 mg
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