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Invitrogen™ K-Ras (Q61R Mutant) Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5143385
This item is not returnable.
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Beschreibung
Store as concentrated solution. Centrifuge briefly prior to opening vial.
This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily A single amino acid substitution is responsible for an activating mutation The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.
Spezifikation
| K-Ras (Q61R Mutant) | |
| Polyclonal | |
| Unconjugated | |
| P29466, P48729, Q8N752 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 122011, 1452, 834 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot, Immunocytochemistry | |
| 0.54 mg/mL | |
| PBS with 1% BSA, 20% glycerol and 0.025% Proclin 300; pH 7 | |
| CFC2; c-Ki-ras2; C-K-RAS; KI-RAS; K-Ras; KRAS proto-oncogene, GTPase; KRAS1; KRAS2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; NS; NS3; RALD; RASK2 | |
| Carrier-protein conjugated synthetic peptide surrounding mutant Q61R of human K-Ras. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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