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Invitrogen™ KAL1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5116679
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Description
Positive Samples: SH-SY5Y, Mouse lung Immunogen sequence: LEVKWSSKFN ISIEPVIYVV QRRWNYGIHP SEDDATHWQT VAQTTDERVQ LTDIRPSRWY QFRVAAVNVH GTRGFTAPSK HFRSSKDPSA PPAPANLRLA N.
KAL1 (Anosmin-1) an extracellular matrix-associated glycosylated protein, have been linked with Kallmann Syndrome (KS), an X-linked genetic disorder characterized by loss of smell caused by abnormal olfactory bulb development and delayed puberty caused by disrupted migration of the gonadotropin-releasing hormone neuron. Anosmin-1 has been shown to directly bind FGFR1 via its N-terminal cysteine-rich domain, whey-acidic protein-like domain, and its first FnIII repeat with the D2 and D3 ectodomains of FGFR1. It is thought that Anosmin-1 can modulate FGFR1 signaling and have opposing effects on the formation and activation of FGF2-FGFR1-heparing complex.
Specifications
| KAL1 | |
| Polyclonal | |
| Unconjugated | |
| ANOS1 | |
| Adhesion molecule-like X-linked; ADMLX; ANOS1; anosmin; anosmin 1; Anosmin1; anosmin-1; HH1; HHA; KAL; KAL1; KALIG1; KALIG-1; Kallmann syndrome interval gene 1; kallmann syndrome protein; Kallmann syndrome-1 sequence (anosmin-1); KMS; WAP four-disulfide core domain 19; WFDC19 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 3730 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 2.24 mg/mL | |
| PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 | |
| P23352 | |
| ANOS1 | |
| Synthetic peptide. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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