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Invitrogen™ KBTBD3 Polyclonal Antibody

Description
Immunogen sequence: GSQDIKSLLD VESYNPLSRE WTSVSPLPRG IYYPEASACQ NIIYVLGSEV EIADAFNPSL DCFFKYNATT DQWSELVAEF GQFFHATLIK AVPVNCTLYI CDLSTYKVYS FCPDTCVWKG EGSFECAGFN AGAIGIEDKI YILGGDYAPD EITDEVQVYH SSRSEWEEVS PMPRALTEFY CQVIQFNKYR DPWYSNHF; Positive Samples: PC-3.
The BTB (Broad-Complex, Tram track and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KBTBD3 (kelch repeat and BTB domain-containing protein 3), also known as BKLHD3, is a 608 amino acid protein that contains one BACK (BTB/Kelch associated) domain, one BTB (POZ) domain and five kelch repeats. The gene encoding KBTBD3 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
Specifications
Specifications
| Antigen | KBTBD3 |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Concentration | 0.48 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | KBTBD3 |
| Gene Accession No. | Q8NAB2 |
| Gene Alias | 2200003A07Rik; Bklhd3; BTB and kelch domain containing 3; BTB and kelch domain-containing protein 3; Kbtbd3; kelch repeat and BTB (POZ) domain containing 3; kelch repeat and BTB domain containing 3; kelch repeat and BTB domain-containing protein 3 |
| Gene Symbols | KBTBD3 |
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