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KCC3 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Thermo Scientific PA556975
Additional Details : Weight : 0.02000kg
Description
Immunogen sequence: RVRFSSRESV PETSRSEPMS EMSGATTSLA TVALDPPSDR TSHPQDVIED LSQNSITGEH SQLLDDGHKK ARNAYLNNSN YEEGDE Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 93%.
SLC12A6 is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy.Specifications
| KCC3 | |
| Polyclonal | |
| Unconjugated | |
| SLC12A6 | |
| 9530023I19Rik; ACCPN; DKFZP434D2135; Electroneutral potassium-chloride cotransporter 3; furosemide-sensitive KCl cotransporter 3; gaxp; Kcc3; KCC3A; KCC3B; K-Cl cotransporter 3; potassium chloride cotransporter 3; potassium chloride cotransporter KCC3a-S3; potassium-chloride transporter-3a; potassium-chloride transporter-3b; SLC12A6; solute carrier family 12 (potassium/chloride transporter), member 6; solute carrier family 12 (potassium/chloride transporters), member 6; solute carrier family 12 member 6; solute carrier family 12, member 6 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 9990 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunocytochemistry, Immunohistochemistry (Paraffin) | |
| 0.1 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q9UHW9 | |
| SLC12A6 | |
| Recombinant protein corresponding to Human KCC3 | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
Research Use Only