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Invitrogen™ KCTD13 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA560403
This item is not returnable.
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Description
Immunogen sequence: RGEDEENREH RVRRIHVRRH ITHDERPHGQ QIVFKD Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.
Cytochrome P450 super family proteins are monooxygenases which catalyze multiple biochemical reactions involved in drug metabolism and synthesis of cholesterol, steroids and lipids. CYP4F3, a 60KDa protein, is a novel member of this family. It consists of a conserved heme-binding domain near the C-terminus and catalyzes the u-hydroxylation of LTB4. CYP4F3 is localized in the ER and plays a vital role in the inactivation of LTB4 and controlling inflammation. CYP4F3 exists in two functionally distinct isoforms: CYP4F3A, a neutrophil isoform, is particularly expressed in neutrophils and myeloid cells and catalyzes the microsomal u-hydroxylation of LTB4. It interacts with CD11b and myeloperoxidase on myeloid cells and regulates cellular development in bone marrow. CYP4F3B, a liver isoform, catalyzes the conversion of arachidonic acid to 20-HETE, a potent activator of PKC. Itrole hasbeen implicatedin cell proliferation, vascular tone and natriuresis.
Specifications
| KCTD13 | |
| Polyclonal | |
| Unconjugated | |
| KCTD13 | |
| 1500003N18Rik; AV259508; BACURD1; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1; BTB/POZ domain-containing protein KCTD13; CTD-2574D22.4; FKSG86; hBACURD1; Kctd13; PDIP1; PDIP1alpha; Poldip1; Polymerase delta-interacting protein 1; potassium channel tetramerisation domain containing 13; potassium channel tetramerization domain containing 13; PP6832; TNFAIP1-like protein; tumor necrosis factor alpha-inducible protein PDIP1; Unknown (protein for MGC:134443) | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 253980 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 0.1 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q8WZ19 | |
| KCTD13 | |
| Recombinant protein corresponding to Human KCTD13. Recombinant protein control fragment (Product #RP-98771). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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