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Tocris Bioscience™ KG 5
GREENER_CHOICE

PDGFRβ, B-Raf, c-Raf, FLT3 and KIT inhibitor

Brand:  Tocris Bioscience™ 5260/50

Encompass

Product Code. 15766626

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Description

Description

KG 5 is a PDGFRβ and B-Raf allosteric inhibitor. Also inhibits c-Raf, FLT3 and KIT. Disrupts blood vessel formation in zebrafish embryos and inhibits angiogenesis in a mouse angiogenesis model. Inhibits growth of renal and pancreatic tumors in mice. Also arrests cells in prometaphase. Orally available.
Specifications

Specifications

2-(Methylthio)-6-[4-[5-[[3-(trifluoromethyl)phenyl]amino]-1H-1,2,4-triazol-3-yl]phenoxy]-4-pyrimidinamine
877874-85-6
50 mg
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