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Invitrogen™ KIAA1530 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA528497
This item is not returnable.
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Description
Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji. Predicted reactivity: Mouse (83%), Rat (83%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by KIAA1530 appears to be involved in ubiquitination and dephosphorylation of RNA polymerase II subunits that stall after UV irradiation. The encoded protein interacts with several members of the nucleotide excision repair complex, and is thought to be involved in the transcription-coupled nucleotide excision repair (TC-NER) pathway to help remove lesions in the DNA that block transcription. Defects in KIAA1530 can cause UV-sensitive syndrome 3. Alternative splicing results in multiple transcript variants.
Specifications
| KIAA1530 | |
| Polyclonal | |
| Unconjugated | |
| UVSSA | |
| KIAA1530; UV stimulated scaffold protein A; UVSS3; UVSSA; UV-stimulated scaffold protein A | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 57654 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7 | |
| Q2YD98 | |
| UVSSA | |
| Recombinant protein encompassing a sequence within the N-terminus region of human UVSSA. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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