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  6. KLHDC3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

KLHDC3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16872324 Shop All Proteintech Products
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20 μL
150 μL
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16872324 20 μL 20µL
16862324 150 μL 150µL
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Product Code. 16872324 Supplier Proteintech Supplier No. 139051AP20UL

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Description

Rabbit Polyclonal Antibody

This antibody specifically reacts with the 55 kDa KLHDC3 protein.

The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. The Kelch domain-containing protein 3 (KLHDC3), also designated PEAS, contains 5 Kelch repeats and may be involved in meiotic recombination process. The gene encoding KLHDC3 maps to chromosome 6, which contains around 1, 200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda, Parkinson′s disease, Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. KLHDC3 protein is mainly expressed in cytoplasm, also found in meiotic chromatin.

Specifications

Antigen KLHDC3
Applications Immunohistochemistry (Paraffin), Immunocytochemistry, Immunofluorescence, Western Blot
Classification Polyclonal
Concentration 0.52 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene KLHDC3
Gene Accession No. Q6AYI2, Q8VEM9, Q9BQ90
Gene Alias hPEAS, kelch domain containing 3, KLHDC3, PEAS, Protein Peas, RP1 20C7.3
Gene Symbols Klhdc3
Host Species Rabbit
Immunogen KLHDC3 Fusion Protein Ag4879
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116138, 363192, 71765
Target Species Mouse, Rat, Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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