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Invitrogen™ KMT2C Polyclonal Antibody

Description
Immunogen sequence: DTQLKEEYIC MYCKHLGAEM DRLQPGEEVE IAELTTDYNN EMEVEGPEDQ MVFSEQAANK DVNGQESTPG IVPDAVQVHT EEQQKSHPSE SL Antigen sequence identity: Mouse 67%; Rat 67%.
Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Central component of the MLL2/3 complex, a coactivator complex of nuclear receptors, involved in transcriptional coactivation. KMT2C/MLL3 may be a catalytic subunit of this complex. May be involved in leukemogenesis and developmental disorder.
Specifications
Specifications
| Antigen | KMT2C |
| Applications | Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.4 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | KMT2C |
| Gene Accession No. | Q8NEZ4 |
| Gene Alias | 2.1.1.43; ALR-like protein; HALR; Histone-lysine N-methyltransferase 2C; histone-lysine N-methyltransferase MLL3; histone-lysine N-methyltransferase, H3 lysine-4 specific; homologous to ALR protein; KIAA1506; KMT2C; lysine (K)-specific methyltransferase 2C; lysine methyltransferase 2C; Lysine N-methyltransferase 2C; MLL3; Myeloid/lymphoid or mixed-lineage leukemia protein 3 |
| Gene Symbols | KMT2C |
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