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Epredia™ Lab Vision™ Estrogen Receptor Ab-14, Mouse Monoclonal Antibody
Ensure accurate, reproducible results in immunohistochemistry and western blotting experiments with Epredia™ Estrogen Receptor Ab-14, Mouse Monoclonal Antibody.
Brand: Epredia™ MS-750-S
Additional Details : Weight : 0.00100kg
Description
The ER gene consists of more than 140kb of genomic DNA divided into 8 exons and is translated into a protein with six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.Host Species: Mouse
Clone: 1D5 + 6F11
Isotype: IgG1 + IgG1/κ
Species Reactivity: Human and Rat. Others not known.
Epitope: Not determined
Immunogen: Recombinant human estrogen receptor protein
Molecular Weight: 67 kDa
Positive Control: MCF-7 cells, Breast CA
Cellular Localization: Nuclear
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
Specifications
| Estrogen Receptor Ab-14 | |
| Monoclonal | |
| Unconjugated | |
| Mouse | |
| 1 mL | |
| Oncogenesis | |
| Human, Rat | |
| Concentrated |
| Immunohistochemistry (Paraffin), Western Blot | |
| 1D5 + 6F11 | |
| WB 1:50-1:100 for 2h RT; IH 1:100-1:200 for 30 min | |
| Recombinant human estrogen receptor protein | |
| ASR, IVD | |
| Primary | |
| Store vial at 4deg.C. When stored at 2 to 8deg.C, | |
| IgG1 |