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Thermo Scientific™ Lab Vision™ Estrogen Receptor Ab-14, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in immunohistochemistry and western blotting experiments with Thermo Scientific™ Estrogen Receptor Ab-14, Mouse Monoclonal Antibody.

Merk:  Thermo Scientific™ MS-750-S

Overige gegevens : Gewicht : 1.00000kg

 Bekijk meerdere types van dit product via de

Produktcode. 12692247

  • € 747.09 / 1 ml


Geschatte verzenddatum
bij leverancier 24-09-2019
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Beschrijving

Beschrijving

The ER gene consists of more than 140kb of genomic DNA divided into 8 exons and is translated into a protein with six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

Host Species: Mouse

Clone: 1D5 + 6F11

Isotype: IgG1 + IgG1/κ

Species Reactivity: Human and Rat. Others not known.

Epitope: Not determined

Immunogen: Recombinant human estrogen receptor protein

Molecular Weight: 67 kDa

Positive Control: MCF-7 cells, Breast CA

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
Specificatie

Specificatie

Estrogen Receptor Ab-14
Monoclonal
Unconjugated
Culture Supernatant with Azide
Murine
IgG1
ASR, IVD
Store vial at 4deg.C. When stored at 2 to 8deg.C,
Primary
Human, Rat
Immunohistochemistry (Paraffin), Western Blot
1D5 + 6F11
WB 1:50-1:100 for 2h RT; IH 1:100-1:200 for 30 min
Concentrated
Recombinant human estrogen receptor protein
1mL
Oncogenesis
Primary
Monoclonal
Video's
Documentatie