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p53 Ab-5 Mouse Monoclonal Antibody, Epredia™
Achieve accurate, reproducible results with the Epredia™ p53 Ab-5, Mouse Monoclonal Antibody.
Brand: Epredia MS-186-R7
Additional Details : Weight : 0.01200kg
Description
p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.Host Species: Mouse
Clone: DO-7
Isotype: IgG2b/κ
Species Reactivity: Human, Monkey, Cow. Others not known.
Epitope: aa 37-45
Immunogen: Recombinant human wild-type p53 protein expressed in E. coli
Molecular Weight: 53kDa
Positive Control: SKBR-3 or MDA-231 cells, Colon CA
Cellular Localization: Nuclear
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunofluorescence
- Immunoprecipitation (Denatured verified)
- Flow Cytometry
Specifications
| p53 Ab-5 | |
| Monoclonal | |
| Unconjugated | |
| Recombinant human wild-type p53 protein expressed in E. coli | |
| IVD | |
| Primary | |
| Prediluted |
| Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| DO-7 | |
| Mouse | |
| 7 mL | |
| Cancer and Tumor Biology | |
| Bovine, Human, Non-human Primate | |
| IgG2b κ |