TTF-1 (Thyroid Transcription Factor-1) Ab-1 Mouse Monoclonal Antibody, Epredia™

Description

TTF-1(Thyroid transcription factor-1) is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. TTF-1 is detected in primary lung adenocarcinomas and small cell carcinomas and is absent in colon and breast carcinomas. Staining with TTF-1 antibody is useful for distinguishing between tumors of lung and non-lung origin.

Host Species: Mouse

Clone: 8G7G3/1

Isotype: IgG1/κ

Species Reactivity: Human, Mouse and Rat. Shows a broad species reactivity.

Epitope: Not determined

Immunogen: Rat TTF-1 recombinant protein

Molecular Weight: 40kDa

Positive Control: MAD109 cells, normal thyroid or lung

Cellular Localization: Nuclear

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Immunofluorescence