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Invitrogen™ Lamin B Receptor Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA542709
This item is not returnable.
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Description
Peptide sequence: GANSQKNAFR KNPSDPKLAH LKTIHTSTGK NLLVSGWWGF VRHPNYLGDL Sequence homology: Cow: 86%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 93%; Rat: 100%; Yeast: 77%; Zebrafish: 79%.
The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
Specifications
| Lamin B Receptor | |
| Polyclonal | |
| Unconjugated | |
| LBR | |
| 3-beta-hydroxysterol Delta (14)-reductase; AI505894; C-14 sterol reductase; C14SR; Delta(14)-sterol reductase LBR; delta(14)-sterol reductase LBR; lamin-B receptor; Delta-14-SR; DHCR14B; FLJ43126; ic; ichthyosis; integral nuclear envelope inner membrane protein; lamin B receptor; lamin-B receptor; lamin-b receptor-like protein; Lbr; LMN2R; MGC9041; NBP60; PHA; PRO0650; sb:cb406; Sterol C14-reductase; TDRD18; tudor domain containing 18; wu:fb75h08; wu:fc47b04; wu:fd36b07; zgc:86649 | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 3930 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Western Blot | |
| 0.5 mg/mL | |
| PBS with 2% sucrose and 0.09% sodium azide | |
| Q14739 | |
| LBR | |
| Synthetic peptide directed towards the middle region of human LBR. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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