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Invitrogen™ Laminin alpha-5 Monoclonal Antibody (CL3118)

Product Code. 15749300 Shop All Thermo Scientific Products
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Quantity:
100 μL
Unit Size:
100µL
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15749300 100 μL 100µL
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Product Code. 15749300 Supplier Invitrogen™ Supplier No. MA524649

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Description

Mouse Monoclonal Antibody

Immunogen sequence: LNLSSIILDV NQDRLTQRAI EASNAYSRIL QAVQAAEDAA GQALQQADHT WATVVRQGLV DRAQQLLANS TALEEAMLQE QQRLGLVWAA L Binds to an epitope located within the peptide sequence RQGLVDRAQQ as determined by overlapping synthetic peptides. Highest antigen sequence indentity to the following orthologs: Rat - 68%, Mouse - 62%.

Components of the extracellular matrix exert myriad effects on tissues throughout the body. In particular, the laminins, a family of heterotrimeric extracellular glycoproteins, affect tissue development and integrity in such diverse organs as the kidney, lung, skin, and nervous system. It is thought that laminins mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminins function as heterotrimeric complexes of alpha, beta, and gamma chains, with each chain type representing a different subfamily of proteins. The protein encoded by this gene belongs to the alpha subfamily of laminin chains and is a major component of basement membranes. Two transcript variants encoding different isoforms have been found for this gene, but the full-length nature of one of them has not been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Laminin alpha-5
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone CL3118
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene LAMA5
Gene Accession No. O15230
Gene Alias [a]5; AA408760; AA408762; AI853660; KIAA0533; KIAA1907; LAMA5; laminin alpha-5 chain; laminin subunit alpha 5; laminin subunit alpha-5; laminin, alpha 5; laminin-10 subunit alpha; Laminin-11 subunit alpha; laminin-15 subunit alpha; laminin-511; mKIAA0533; RP11-157P1.6
Gene Symbols LAMA5
Host Species Mouse
Immunogen Recombinant protein fragment of Human LAMA5 (Product #RP-108178)
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3911
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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