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Invitrogen™ LAMTOR4 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA578680
This item is not returnable.
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Description
Positive Control: HeLa, SKNSH Predicted Reactivity: Mouse (95%), Rat (96%), Bovine (97%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
LAMTOR4 is a part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. LAMTOR4 is activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. LAMTOR4 is activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated.
Specifications
| LAMTOR4 | |
| Polyclonal | |
| Unconjugated | |
| LAMTOR4 | |
| 0910001L09Rik; AV006840; C7orf59; Lamtor4; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4; late endosomal/lysosomal adaptor, MAPK and MTOR activator 4; ragulator complex protein LAMTOR4; Ragulator complex protein LAMTOR4, N-terminally processed; RGD1309735; UPF0539 protein C7orf59; UPF0539 protein C7orf59 homolog | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 389541 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot | |
| 2.74 mg/mL | |
| PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7 | |
| Q0VGL1 | |
| LAMTOR4 | |
| Full length human LAMTOR4 recombinant protein. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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