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Invitrogen™ LAMTOR4 Polyclonal Antibody

Product Code. 15782231 Shop All Thermo Scientific Products
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100 μL
Unit Size:
100µL
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15782231 100 μL 100µL
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Product Code. 15782231 Supplier Invitrogen™ Supplier No. PA554301

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MTSALTQGLE RIPDQLGYLV LSEGAVLASS GDLENDEQAA SAISELVSTA CGFRLHRGMN VPFKRLSVVF GEHTLLVTVS GQRVFVVKRQ NRGREPIDV Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 97%.

LAMTOR4 is a part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. LAMTOR4 is activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. LAMTOR4 is activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LAMTOR4
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene LAMTOR4
Gene Accession No. Q0VGL1
Gene Alias 0910001L09Rik; AV006840; C7orf59; Lamtor4; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4; late endosomal/lysosomal adaptor, MAPK and MTOR activator 4; ragulator complex protein LAMTOR4; Ragulator complex protein LAMTOR4, N-terminally processed; RGD1309735; UPF0539 protein C7orf59; UPF0539 protein C7orf59 homolog
Gene Symbols LAMTOR4
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human LAMTOR4. Recombinant protein control fragment (Product #RP-92832).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 389541
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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