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Invitrogen™ LAP (Latency Associated Peptide) Polyclonal Antibody
Goat Polyclonal Antibody
Brand: Invitrogen™ PA5143311
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Description
Additional Information: This antibody is expected to recognize the part representing the latency-associated peptide. This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
TGF beta-1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines, found almost ubiquitously in tissues. Transforming growth factor (TGF)-b is stored in the extracellular matrix as a latent complex with its prodomain. Activation of TGF-b1 requires the binding of aV integrin to an RGD sequence in the prodomain and exertion of force on this domain, which is held in the extracellular matrix by latent TGF-b binding proteins. Latent forms are complexes of TGF-beta, an aminoterminal portion of the TGF-beta precursor, designated TGF-LAP (TGF-latency associated peptide), and a specific binding protein, known as LTBP.
Specifications
| LAP (Latency Associated Peptide) | |
| Polyclonal | |
| Unconjugated | |
| TGFB1 | |
| CED; DPD1; LAP; latency-associated peptide; prepro-transforming growth factor beta-1; regulatory protein; TGFB; Tgfb1; Tgfb-1; TGFbeta; TGF-beta 1; TGFbeta1; TGF-beta1; TGF-beta-1; transforming growth factor beta 1; transforming growth factor beta-1; Transforming growth factor beta-1 proprotein; transforming growth factor, beta 1; transforming growth factor-beta 1 | |
| Goat | |
| Ammonium Sulfate Precipitation | |
| RUO | |
| 7040 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Western Blot | |
| 0.5 mg/mL | |
| TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
| P01137 | |
| TGFB1 | |
| Peptide with sequence C-STYTSGDQKTIKSTR (aa 257-271). | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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