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Description
Immunogen sequence: VRWDTFPLGR MPGQTEDPAE LMLENYDTMY LLDQPVLEQR LEPSTCKTDT LGLSCGVGSG NCSNSSSSNF EGLLWSQGQL HGLKTG Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 67%.
Involved in the biogenesis of the 60S ribosomal subunit. Required for maturation of the 28S rRNA. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.
Specifications
Specifications
| Antigen | LAS1L |
| Applications | Immunohistochemistry (Paraffin) |
| Classification | Polyclonal |
| Concentration | 0.2 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | Las1l |
| Gene Accession No. | Q9Y4W2 |
| Gene Alias | 1810030A06Rik; 5830482G23Rik; dJ475B7.2; LAS1 like ribosome biogenesis factor; LAS1 like, ribosome biogenesis factor; LAS1L; Las1-like; LAS1-like (S. cerevisiae); LAS1-like, ribosome biogenesis factor; MSTP060; Protein LAS1 homolog; RGD1565755; Ribosomal biogenesis protein LAS1L |
| Gene Symbols | Las1l |
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Product Title
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