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Invitrogen™ LAT Polyclonal Antibody
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Product Code. 16387164
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. Quantity unitSize
16387164 100 μL 100µL
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Product Code. 16387164 Supplier Invitrogen™ Supplier No. PA578472

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Description

Rabbit Polyclonal Antibody

Positive Control: Jurkat, Jurkat membrane extract Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

LAT (Linker for Activation of T cells) is a 36-38 kDa double-palmitoylated transmembrane adaptor protein expressed by T cells, pre-B cells, NK cells, mast cells and platelets. After immunoreceptor triggering, LAT becomes multiply tyrosine-phosphorylated by Syk-, Src-, or Tec-family kinases, providing docking sites for downstream signaling molecules. LAT is essential for TCR-dependent T cell- and FcepsilonRI-dependent mast cell activation, as well as for maturation of early thymocytes. It is also involved in NK cell signaling and platelet activation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LAT
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.41 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene LAT
Gene Accession No. O43561, O54957, O70601
Gene Alias 36 kDa phospho-tyrosine adapter protein; 36 kDa phospho-tyrosine adaptor protein; Lat; LAT1; linker for activation of T cells; linker for activation of T cells, transmembrane adaptor; linker for activation of T-cells; linker for activation of T-cells family member 1; linker protein; p36-38; pp36
Gene Symbols LAT
Host Species Rabbit
Immunogen Synthetic peptide encompassing a sequence within the Intracellular domain of human LAT. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16797, 27040, 81511
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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