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Invitrogen™ LEPREL1 Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA552480
This item is not returnable.
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Description
Immunogen sequence: LHYDYLQFAY YRVGEYVKAL ECAKAYLLCH PDDEDVLDNV DYYESLLDDS IDPASIEARE DLTMFVKRHK LESELIKSAA EGLGFSYTEP NYWIRYGGRQ DENRVPSGVN VEGAEVHGFS MGKKLSPKID RDLREGGPLL Y Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 89%.
This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Specifications
| LEPREL1 | |
| Polyclonal | |
| Unconjugated | |
| P3h2 | |
| 4832416N06; AW553532; leprecan-like 1; leprecan-like protein 1; Leprel1; MCVD; Mlat4; myxoid liposarcoma associated protein 4; myxoid liposarcoma-associated protein 4; P3h2; procollagen-proline 3-dioxygenase 2; prolyl 3-hydroxylase 2; prolyl 3-hydroxylase 3 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 288016, 55214 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 0.1 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q4KLM6, Q8IVL5 | |
| P3h2 | |
| Recombinant protein corresponding to Human LEPREL1. Recombinant protein control fragment (Product #RP-89685). | |
| 100 μL | |
| Primary | |
| Human, Rat | |
| Antibody | |
| IgG |
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