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Invitrogen™ LGI1 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA520506

Product Code. 12868682

  • € 520.00 / 100µg

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Description

Description

A suggested positive control is mouse brain tissue lysate. PA5-20506 can be used with blocking peptide PEP-0626.

The leucine-rich, glioma inactivated gene 1 (LGI1) was first identified as a candidate tumor suppressor gene for glioma and may play a role in other cancers. LGI1 is a member of a family of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 serves as a ligand to ADAM22, a metalloprotease localized at the synapse. Mutations in LGI1 account for nearly half of autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Two isoforms of LGI1 are known to exist.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

LGI1
Polyclonal
Unconjugated
LGI1
ADLTE; ADPAEF; ADPEAF; BB130740; EPITEMPIN; Epitempin 1; Epitempin-1; EPT; ETL1; IB1099; leucine rich glioma inactivated 1; leucine-rich glioma inactivated 1; leucine-rich glioma-inactivated protein 1; leucine-rich repeat LGI family, member 1; leucine-rich, glioma inactivated 1; LGI1; OTTHUMP00000020121; OTTHUMP00000020122; UNQ775/PRO1569
Rabbit
Antigen affinity chromatography
RUO
252892, 56839, 9211
Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Liquid
Western Blot
1 mg/mL
PBS with 0.02% sodium azide
O95970, Q8K4Y5, Q9JIA1
LGI1
A 13 amino acid peptide from near the amino terminus of human LGI1.
100 μg
Primary
Human, Mouse, Rat
Antibody
IgG
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