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Invitrogen™ LIMK1 Recombinant Rabbit Monoclonal Antibody (23GB6425), Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA553046
This item is not returnable.
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Description
LIMK1 is a serine/threonine kinase involved in regulation of actin cytoskeletal changes via phosphorylation of cofilin. LIMK1 has also been implicated in brain development. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is likely to be a component of an intracellular signaling pathway and may be involved in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome.
Specifications
| LIMK1 | |
| Recombinant Monoclonal | |
| Unconjugated | |
| LIMK1 | |
| EC 2.7.11.1; kinase LIMK1; KIZ-1; LIM domain kinase 1; lim kinase 1; LIM motif-containing protein kinase; LIM motif-containing protein kinase 1; LIM-domain containing protein kinase 1; LIM-domain containing, protein kinase; LIM-domain containing, protein kinase 1; Limk; LIMK1; LIMK-1 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 16885, 3984 | |
| -20°C | |
| Liquid |
| Western Blot, Immunocytochemistry | |
| 23GB6425 | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P53667, P53668 | |
| LIMK1 | |
| A synthesized peptide derived from human LIM Kinase 1 (1-57AA). | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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