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Invitrogen™ LIMS1 Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA530240
Description
Recommended positive controls: A549, HeLa, HCT116. Predicted reactivity: Human (99%), Mouse (99%), Rat (99%), Zebrafish (95%), Xenopus laevis (97%), Pig (98%), Chicken (95%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.
Specifications
| LIMS1 | |
| Polyclonal | |
| Unconjugated | |
| LIMS1 | |
| 2310016J22Rik; 4921524A02Rik; AI507642; AU021743; AW551584; C430041B13Rik; LIM and senescent cell antigen-like domains 1; LIM and senescent cell antigen-like-containing domain protein 1; LIM zinc finger domain containing 1; LIMS1; Lims1l; LIM-type zinc finger domains 1; Particularly interesting new Cys-His protein 1; PINCH; PINCH1; PINCH-1; renal carcinoma antigen NY-REN-48; RGD1560732; senescent cell antigen | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 3987 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 0.88 mg/mL | |
| 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7 | |
| P48059 | |
| LIMS1 | |
| Recombinant protein encompassing a sequence within the center region of human LIMS1. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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