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Invitrogen™ LKB1 Monoclonal Antibody (206R24)
Mouse Monoclonal Antibody
Marca: Invitrogen™ AHO1392
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Descripción
LKB1 Monoclonal Antibody for Western Blot, ICC/IF, IHC (P)
LKB1 (also known as STK11 - Serine/threonine-protein kinase STK11), a member of the serine/threonine kinase family, is a tumor suppressor. LKB1 physically associates with p53 and regulates specific p53 dependent apoptosis pathways. LKB1 is present in both the cytoplasm and nucleus of living cells and translocates to mitochondria during apoptosis. LKB1 functions as a master upstream protein kinase, regulating AMPK related kinases as well as AMPK. Mutations in LKB1 gene are associated with Peutz Jeghers syndrome.
Especificaciones
| LKB1 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with 1% BSA and 0.1% sodium azide; pH 7.2 | |
| D4AE59, Q15831, Q9WTK7 | |
| STK11 | |
| Recombinant fragment of human LKB1 expressed in E. coli. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat, Monkey | |
| Antibody | |
| IgG2a κ |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 206R24 | |
| Unconjugated | |
| STK11 | |
| AA408040; CAMK group; CAMKL family; hLKB1; liver kinase B1; Liver kinase B1 homolog; LKB 1; LKB1; LKB-1; LKB1(S); Par-4; PJS; polarization-related protein LKB1; R75140; renal carcinoma antigen NY-REN-19; serine/threonine kinase 11; serine/threonine-protein kinase 11; serine/threonine-protein kinase LKB1; serine/threonine-protein kinase STK11; STK11 | |
| Mouse | |
| Purified | |
| RUO | |
| 20869, 314621, 6794 | |
| -20°C | |
| Liquid |
Título del producto
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