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LMAN1 Monoclonal Antibody (OTI1E3), TrueMAB™, OriGene
Description
The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.
Specifications
Specifications
| Antigen | LMAN1 |
| Applications | Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot |
| Classification | Monoclonal |
| Clone | OTI1E3 |
| Concentration | 0.24 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 1% BSA, 50% glycerol and 0.02% sodium azide |
| Gene | LMAN1 |
| Gene Accession No. | P49257 |
| Gene Alias | ERGIC-53, ERGIC53, F5F8D, FMFD1, MCFD1, MR60, gp58 |
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Product Title
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